BDBM50283045 (Z)-7-[(2S,3S,4S)-4-(Biphenyl-4-ylmethoxy)-2-pyridin-3-yl-tetrahydro-thiophen-3-yl]-hept-5-enoic acid::CHEMBL65161

SMILES OC(=O)CCC\C=C/C[C@H]1[C@@H](CS[C@@H]1c1cccnc1)OCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=AVFPODQCTNAKHD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283045   

TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283045((Z)-7-[(2S,3S,4S)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...)
Affinity DataIC50: 43nMAssay Description:In vitro inhibition of thromboxane synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetThromboxane A2 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283045((Z)-7-[(2S,3S,4S)-4-(Biphenyl-4-ylmethoxy)-2-pyrid...)
Affinity DataIC50: 228nMAssay Description:In vitro thromboxane receptor antagonist activity was determined by inhibition of U-46619 induced aggregation of washed human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article