BDBM50283315 2-Ethyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbonylaminosulphonyl)-biphenyl-4-ylmethyl)-6-(ethylaminocarbonylamino)-3H-quinazolin-4-one::CHEMBL306361

SMILES CCNC(=O)Nc1ccc2nc(CC)n(Cc3ccc(cc3F)-c3ccccc3S(=O)(=O)NC(=O)OCCC3CC3)c(=O)c2c1

InChI Key InChIKey=NPBJGLQTLJRBIP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50283315   

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283315(2-Ethyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...)
Affinity DataIC50: 0.800nMAssay Description:In vivo inhibitory concentration against AT2 receptor of rat adrenal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50283315(2-Ethyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...)
Affinity DataIC50: 0.730nMAssay Description:In vivo inhibitory concentration against Angiotensin II receptor, type 1 of rabbit aorta membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-1 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283315(2-Ethyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...)
Affinity DataIC50: 12nMAssay Description:In vivo inhibitory concentration against Angiotensin II receptor, type 1 of human adrenal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50283315(2-Ethyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...)
Affinity DataIC50: 9.80nMAssay Description:In vivo inhibitory concentration against AT2 receptor of human adrenal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

LigandPNGBDBM50283315(2-Ethyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...)
Affinity DataIC50: 0.640nMAssay Description:In vivo inhibitory concentration against Angiotensin II receptor, type 1 of rat adrenal membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50283315(2-Ethyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbo...)
Affinity DataIC50: 0.560nMAssay Description:In vivo inhibitory concentration against Angiotensin II, type 2 of rat midbrain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article