BDBM50283363 CHEMBL312809::{(S)-1-[1-Benzyl-4-(3,4-dihydro-1H-isoquinolin-2-yl)-3,3-difluoro-2,4-dioxo-butylcarbamoyl]-2-methyl-propyl}-carbamic acid benzyl ester

SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)N1CCc2ccccc2C1

InChI Key InChIKey=ZDQOXACMPIJOIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50283363   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50283363({(S)-1-[1-Benzyl-4-(3,4-dihydro-1H-isoquinolin-2-y...)
Affinity DataIC50: 50nMAssay Description:Compound was tested for inactivation of purified HIV-1 protease in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article