BDBM50283687 CHEMBL4165684

SMILES ONC(=O)c1ccc(CCN2C(=O)c3cccc4c(ccc(C2=O)c34)N2CCOCC2)cc1

InChI Key InChIKey=CVFBZTABCOVCDI-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50283687   

TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50283687(CHEMBL4165684)
Affinity DataIC50: 139nMAssay Description:Inhibition of human recombinant full-length HDAC6 expressed in baculovirus infected Sf9 cells using Boc-Lys(acetyl)-AMC as substrate after 30 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50283687(CHEMBL4165684)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC4 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50283687(CHEMBL4165684)
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibition of HDAC10 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50283687(CHEMBL4165684)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC11 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50283687(CHEMBL4165684)
Affinity DataIC50: 3.05E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50283687(CHEMBL4165684)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC7 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50283687(CHEMBL4165684)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC5 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50283687(CHEMBL4165684)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant full-length HDAC1 (1 to 482 residues) expressed in baculovirus using Boc-Lys(acetyl)-AMC as substrate after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50283687(CHEMBL4165684)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HDAC9 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50283687(CHEMBL4165684)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant full-length C-terminal GST-tagged HDAC3 expressed in baculovirus infected Sf9 cells using Boc-Lys(acetyl)-AMC as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50283687(CHEMBL4165684)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant full-length C-terminal GST-tagged HDAC2 expressed in baculovirus infected Sf9 cells using Boc-Lys(acetyl)-AMC as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2020
Entry Details Article
PubMed