BDBM50283721 CHEMBL93082::{(S)-1-[(1S,2R)-1-Benzyl-3-((S)-2-tert-butylcarbamoyl-piperidin-1-yl)-2-hydroxy-propylcarbamoyl]-2-carbamoyl-ethyl}-carbamic acid benzyl ester

SMILES CC(C)(C)NC(=O)[C@@H]1CCCCN1C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)OCc1ccccc1

InChI Key InChIKey=WWANYGDDKRZWHZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50283721   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Washington University

Curated by ChEMBL
LigandPNGBDBM50283721({(S)-1-[(1S,2R)-1-Benzyl-3-((S)-2-tert-butylcarbam...)
Affinity DataIC50: 18nMAssay Description:Inhibitory potency against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Washington University

Curated by ChEMBL
LigandPNGBDBM50283721({(S)-1-[(1S,2R)-1-Benzyl-3-((S)-2-tert-butylcarbam...)
Affinity DataIC50: 18nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzyme.(value reported by Roche group)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Washington University

Curated by ChEMBL
LigandPNGBDBM50283721({(S)-1-[(1S,2R)-1-Benzyl-3-((S)-2-tert-butylcarbam...)
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against HIV-1 Protease was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article