BDBM50283976 CHEMBL153201::N-{[7-(4-fluorophenoxy)-2,3-dihydro-1-benzoxepin-4-yl]methyl}-N-hydroxy-N'-methylurea

SMILES CNC(=O)N(O)CC1=Cc2cc(Oc3ccc(F)cc3)ccc2OCC1

InChI Key InChIKey=OOEMHHFSIGXIRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50283976   

LigandPNGBDBM50283976(N-{[7-(4-fluorophenoxy)-2,3-dihydro-1-benzoxepin-4...)
Affinity DataIC50: 100nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on 5-hydroxyeicosapentaenoic acid (5-HETE) productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

LigandPNGBDBM50283976(N-{[7-(4-fluorophenoxy)-2,3-dihydro-1-benzoxepin-4...)
Affinity DataIC50: 130nMAssay Description:In vitro 5-lipoxygenase inhibition in guinea pig PMNs was determined based on LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article