BDBM50284337 CHEMBL4169378

SMILES CCNC(=S)Nc1cc(ncn1)-n1cnc(CCN(CC)CC#C)c1

InChI Key InChIKey=LEJISGXPJIZFIG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50284337   

TargetAmine oxidase [flavin-containing] A(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50284337(CHEMBL4169378)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human MAOA using p-tyramine as substrate preincubated for 15 mins followed by substrate addition measured after 15 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Rat)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50284337(CHEMBL4169378)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of AChE in rat cortex homogenate using acetylthiocholine iodide as substrate after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2020
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Rat)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50284337(CHEMBL4169378)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of BuChE in rat serum using butyrylthiocholine iodide as substrate after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50284337(CHEMBL4169378)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human MAOB using benzylamine as substrate preincubated for 15 mins followed by substrate addition measured after 15 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2020
Entry Details Article
PubMed