BDBM50284443 CHEMBL280456::[4-(2-Ethyl-6,8-dimethyl-imidazo[1,2-b]pyridazin-3-ylmethyl)-phenoxy]-phenyl-acetic acid

SMILES CCc1nc2c(C)cc(C)nn2c1Cc1ccc(OC(C(O)=O)c2ccccc2)cc1

InChI Key InChIKey=SLJYWTLSAGYJBD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284443   

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50284443([4-(2-Ethyl-6,8-dimethyl-imidazo[1,2-b]pyridazin-3...)
Affinity DataIC50: 69nMAssay Description:Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50284443([4-(2-Ethyl-6,8-dimethyl-imidazo[1,2-b]pyridazin-3...)
Affinity DataIC50: 3.00E+3nMAssay Description:Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rat midbrain membrane (AT2 receptor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article