BDBM50284451 CHEMBL279103::[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-propyl-phenoxy]-(2-methoxy-phenyl)-acetic acid

SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)ccc1OC(C(O)=O)c1ccccc1OC

InChI Key InChIKey=MBVFXDSKQKPYPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284451   

TargetType-1 angiotensin II receptor(Rabbit)
TBA

Curated by ChEMBL
LigandPNGBDBM50284451([4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-y...)
Affinity DataIC50: 9.5nMAssay Description:Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rabbit aortic membrane (AT1 receptor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetType-2 angiotensin II receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50284451([4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-y...)
Affinity DataIC50: 1.20E+3nMAssay Description:Tested for its ability to displace the specific binding ligand [125I]-Sar 1,lle8-AlI from rat midbrain membrane (AT2 receptor)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article