BDBM50284491 CHEMBL4176820

SMILES CC(Oc1ccnc(Nc2cnn(CC(C)(C)O)c2)c1)c1cccc(c1)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=NRPGVXXIVNGVKK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284491   

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284491(CHEMBL4176820)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2020
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284491(CHEMBL4176820)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2020
Entry Details Article
PubMed