BDBM50284511 CHEMBL4173466

SMILES CC(Oc1ccnc(NN2CCN(C)CC2)c1)c1cccc(c1)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=VWINXVFVVLWUGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284511   

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284511(CHEMBL4173466)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of recombinant human GST-tagged ROS1 expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2020
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50284511(CHEMBL4173466)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of recombinant human GST-tagged ALK expressed in baculovirus expression system by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2020
Entry Details Article
PubMed