BDBM50284771 (S)-2-((R)-3-(2-Chloro-1H-indol-3-yl)-2-{2-[((2R,6S)-2,6-dimethyl-piperidine-1-carbonyl)-amino]-4-methyl-pentanoylamino}-propionylamino)-hexanoic acid::CHEMBL289410

SMILES CCCC[C@H](NC(=O)[C@@H](Cc1c(Cl)[nH]c2ccccc12)NC(=O)C(CC(C)C)NC(=O)N1[C@@H](C)CCC[C@H]1C)C(O)=O

InChI Key InChIKey=GWMBPTBOMGCAGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50284771   

TargetEndothelin-1 receptor(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50284771((S)-2-((R)-3-(2-Chloro-1H-indol-3-yl)-2-{2-[((2R,6...)
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against 125 I-labeled ET-1 binding to Endothelin A receptor in porcine aortic smooth muscle membranes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article

TargetEndothelin receptor type B(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50284771((S)-2-((R)-3-(2-Chloro-1H-indol-3-yl)-2-{2-[((2R,6...)
Affinity DataIC50: 5.60nMAssay Description:Inhibitory activity against 125 I-labeled ET-1 binding to Endothelin B receptor in porcine cerebellum membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2012
Entry Details Article