BDBM50285031 CHEMBL4172124

SMILES COc1ccc2c(OCc3nnc4sc(nn34)-c3ccc[nH]3)ccnc2c1

InChI Key InChIKey=CXFZCYJLYMEVPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285031   

TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50285031(CHEMBL4172124)
Affinity DataIC50: 16nMAssay Description:Inhibition of GST-tagged human c-MET preincubated for 20 mins followed by [33P]-ATP addition and measured after 2 hrs by Hot-Spot kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50285031(CHEMBL4172124)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human GST-tagged c-MET using KKKSPGEYVNIEFG as substrate preincubated for 20 mins followed by [gamma-33P]ATP addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed