BDBM50285213 5-(4-Fluoro-phenyl)-4-(4-sulfamoyl-phenyl)-thiophene-2-carboxylic acid methyl ester::CHEMBL303870

SMILES COC(=O)c1cc(c(s1)-c1ccc(F)cc1)-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=HCFVSOWMOSKBIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285213   

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285213(5-(4-Fluoro-phenyl)-4-(4-sulfamoyl-phenyl)-thiophe...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against human COX-1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50285213(5-(4-Fluoro-phenyl)-4-(4-sulfamoyl-phenyl)-thiophe...)
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against human COX-2 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article