BDBM50285460 ((1S,2R)-1-Benzyl-3-{(S)-2-tert-butylcarbamoyl-4-[2-(5-ethyl-thiophen-2-yl)-ethyl]-piperazin-1-yl}-2-hydroxy-propyl)-carbamic acid (2R,3R)-2-isopropyl-1,1-dioxo-tetrahydro-1lambda*6*-thiophen-3-yl ester::CHEMBL301193

SMILES CCc1ccc(CCN2CCN(C[C@@H](O)[C@H](Cc3ccccc3)NC(=O)O[C@@H]3CCS(=O)(=O)[C@@H]3C(C)C)[C@@H](C2)C(=O)NC(C)(C)C)s1

InChI Key InChIKey=XWDZZONMJRJYLZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285460   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50285460(((1S,2R)-1-Benzyl-3-{(S)-2-tert-butylcarbamoyl-4-[...)
Affinity DataIC50: 0.760nMAssay Description:Inhibition of HIV-1 ProteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article