BDBM50286542 3-Benzenesulfonyl-5-chloro-2-(4,5-dihydro-thiazol-2-yl)-1H-indole::CHEMBL144742

SMILES Clc1ccc2[nH]c(C3=NCCS3)c(c2c1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=STOLNPJKXCPOCG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50286542   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50286542(3-Benzenesulfonyl-5-chloro-2-(4,5-dihydro-thiazol-...)
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against HIV-1 RT with poly.rC-oligo.dG template primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50286542(3-Benzenesulfonyl-5-chloro-2-(4,5-dihydro-thiazol-...)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibitory activity against K103N/Y181C double mutant of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50286542(3-Benzenesulfonyl-5-chloro-2-(4,5-dihydro-thiazol-...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibitory activity against HIV-2 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article