BDBM50287318 3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(thiazol-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid::CHEMBL289586

SMILES CC(C)(C)Sc1c(CC(C)(C)C(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3nccs3)cc12

InChI Key InChIKey=XTZOFFBASUTOMA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50287318   

TargetArachidonate 5-lipoxygenase-activating protein/Polyunsaturated fatty acid 5-lipoxygenase(Human)
TBA

Curated by ChEMBL

LigandBDBM50287318(3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(thi...)Copy SMILESCopy InChI

Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of calcium ionophore (A23187) stimulated LTB4 formation in human neutrophilsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/20/2010
Entry Details Article
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