BDBM50287325 CHEMBL38884::[3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(quinolin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-prop-(E)-ylideneaminooxy]-acetic acid

SMILES CC(C)(C)Sc1c(CC(C)(C)\C=N\OCC(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc12

InChI Key InChIKey=GCWOCVTZGLAYIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287325   

LigandPNGBDBM50287325([3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qu...)
Affinity DataIC50: 600nMAssay Description:Human whole blood was stimulated with calcium ionophore (A23187) and LTB 4 measured by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

LigandPNGBDBM50287325([3-[3-tert-Butylsulfanyl-1-(4-chloro-benzyl)-5-(qu...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of calcium ionophore (A23187) stimulated LTB4 formation in human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article