BDBM50287376 2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pentanoylamino)-3-methyl-butyl]-3H-benzoimidazole-5-carboxylic acid methyl ester::CHEMBL40351

SMILES COC(=O)c1ccc2nc([nH]c2c1)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)CC(=O)NO

InChI Key InChIKey=JCVSSJUXUIJGBT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287376   

TargetInterstitial collagenase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287376(2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human fibroblast collagenase, matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287376(2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human fibroblast stromelysin, matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetMatrilysin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287376(2-[(S)-1-((R)-2-Hydroxycarbamoylmethyl-4-methyl-pe...)
Affinity DataIC50: 1nMAssay Description:Inhibition of matrilysin, matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article