BDBM50287460 CHEMBL4171547

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(c(s2)C(=O)c2ccccc2C)-c2ccccc2)cc1

InChI Key InChIKey=LITCLGNNSURYND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287460   

TargetNuclear receptor ROR-gamma(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50287460(CHEMBL4171547)
Affinity DataIC50: 10nMAssay Description:Inverse agonist activity at biotinylated RORgammat LBD (unknown origin) assessed as inhibition of N-(2-chloro-6-fluorobenzyl)-N-((2'-methoxy-[1,1'-bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
TargetNuclear receptor ROR-gamma(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50287460(CHEMBL4171547)
Affinity DataIC50: 16nMAssay Description:Inverse agonist activity at APC-labeled RORgammat LBD (unknown origin) assessed as inhibition of N-(2-chloro-6-fluorobenzyl)-N-((2'-methoxy-[1,1'-bip...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed