BDBM50287518 1-(2-Dodecyl-2H-tetrazol-5-yl)-1-phenyl-3-(2,4,6-trimethoxy-phenyl)-urea::CHEMBL49524

SMILES CCCCCCCCCCCCn1nnc(n1)N(C(=O)Nc1c(OC)cc(OC)cc1OC)c1ccccc1

InChI Key InChIKey=VGOIOMRNPIXNIH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50287518   

TargetSterol O-acyltransferase 1(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50287518(1-(2-Dodecyl-2H-tetrazol-5-yl)-1-phenyl-3-(2,4,6-t...)
Affinity DataIC50: 890nMAssay Description:Compound was tested for its ability to penetrate the cell wall and inhibit macrophage ACAT in cell culture using murine IC-21 macrophages (MAI)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetSterol O-acyltransferase 1(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50287518(1-(2-Dodecyl-2H-tetrazol-5-yl)-1-phenyl-3-(2,4,6-t...)
Affinity DataIC50: 61nMAssay Description:Liver Acyl coenzyme A:cholesterol acyltransferase inhibitory activity was determined in vitro using [1-14C]oleolyl-CoA and microsomes isolated from t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article