BDBM50287519 CHEMBL4172084

SMILES Cc1noc(CNC(=O)c2ccc(C)c(c2)S(=O)(=O)Nc2ccc(cc2)-c2cnco2)n1

InChI Key InChIKey=FRSGVKXWGOKXIQ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287519   

LigandPNGBDBM50287519(CHEMBL4172084)
Affinity DataIC50: 32nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50287519(CHEMBL4172084)
Affinity DataIC50: 35nMAssay Description:Inhibition of human ROMK2 expressed in HEK293 cells after 20 mins by Thallos-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed
LigandPNGBDBM50287519(CHEMBL4172084)
Affinity DataKi: >4.00E+4nMAssay Description:Displacement of fluorescent-labelled dofetilide from human ERG expressed in HEK293 cell membrane homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2020
Entry Details Article
PubMed