BDBM50287560 CHEMBL4166521::US11572354, Compound 10a

SMILES C(c1cc2ccccc2[nH]1)n1cncc1-c1ccccc1

InChI Key InChIKey=LBJSTVXBHUOORC-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50287560   

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Health Network

US Patent
LigandPNGBDBM50287560(CHEMBL4166521 | US11572354, Compound 10a)
Affinity DataIC50: 4.44E+3nMAssay Description:A standard reaction mixture (200uL/well) containing 50mM potassium phosphate buffer (pH 6.5), 20 mM ascorbic acid (neutralized with NaOH), 200 ug/mL ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
University Health Network

US Patent
LigandPNGBDBM50287560(CHEMBL4166521 | US11572354, Compound 10a)
Affinity DataIC50: 4.44E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University Health Network

US Patent
LigandPNGBDBM50287560(CHEMBL4166521 | US11572354, Compound 10a)
Affinity DataEC50:  9.12E+3nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2020
Entry Details Article
PubMed