BDBM50288193 CHEMBL4170519

SMILES CNCC(O)COc1ccc(cc1)S(=O)(=O)NCCOc1ccccc1

InChI Key InChIKey=HDYLDYMWRKOIKU-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50288193   

TargetCarbonic anhydrase 2(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288193(CHEMBL4170519)
Affinity DataKi:  15nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288193(CHEMBL4170519)
Affinity DataKi:  82nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288193(CHEMBL4170519)
Affinity DataKi:  85nMAssay Description:Inhibition of recombinant human carbonic anhydrase 9 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288193(CHEMBL4170519)
Affinity DataKi:  183nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288193(CHEMBL4170519)
Affinity DataKi:  6.61E+3nMAssay Description:Displacement of [3H]-CGP12177 from human beta1 ADR expressed in HEK293T cell membranes after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
University of Florence

Curated by ChEMBL
LigandPNGBDBM50288193(CHEMBL4170519)
Affinity DataKi:  2.82E+4nMAssay Description:Displacement of [3H]-CGP12177 from human beta2 ADR expressed in HEK293T cell membrane after 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2020
Entry Details Article
PubMed