BDBM50288984 (S)-4-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propylcarbamoyl]-2-{4-[(2,7-dimethyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-2-fluoro-benzoylamino}-butyric acid::CHEMBL157459

SMILES Cc1nc2cc(C)c(CN(CC#C)c3ccc(C(=O)N[C@@H](CCC(=O)N[C@@H](CCc4nnn[nH]4)C(O)=O)C(O)=O)c(F)c3)cc2c(=O)[nH]1

InChI Key InChIKey=WVIKBEPPBZWZDN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288984   

TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50288984((S)-4-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propylca...)
Affinity DataIC50: 0.820nMAssay Description:Compound was evaluated for the inhibition of Thymidylate synthase in experiment 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetThymidylate synthase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50288984((S)-4-[(S)-1-Carboxy-3-(1H-tetrazol-5-yl)-propylca...)
Affinity DataIC50: 0.820nMAssay Description:Compound was evaluated for the inhibition of Thymidylate synthase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article