BDBM50289075 4-Hydroxy-3-(2-isopropyl-phenylsulfanyl)-6-(4-oxo-4-piperazin-1-yl-butyl)-6-phenyl-5,6-dihydro-pyran-2-one::CHEMBL422197

SMILES CC(C)c1ccccc1SC1C(=O)CC(CCCC(=O)N2CCNCC2)(OC1=O)c1ccccc1

InChI Key InChIKey=LMPVWKYAIVRTNI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50289075   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50289075(4-Hydroxy-3-(2-isopropyl-phenylsulfanyl)-6-(4-oxo-...)
Affinity DataIC50: 564nMpH: 4.7Assay Description:In vitro inhibitory activity against purified HIV-1 protease at a pH of 4.7 and a final enzyme concentration of 0.45-1.1 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article