BDBM50289102 1,2,3,9-Tetrahydro-pyrrolo[2,1-b]quinazoline::CHEMBL2163792::CHEMBL355821

SMILES C1CN2Cc3ccccc3N=C2C1

InChI Key InChIKey=WUFQLZTXIWKION-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50289102   

TargetAcetylcholinesterase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289102(CHEMBL2163792 | CHEMBL355821 | 1,2,3,9-Tetrahydro-...)
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibitory activity against acetylcholinesterase in human RBCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetAcetylcholinesterase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289102(CHEMBL2163792 | CHEMBL355821 | 1,2,3,9-Tetrahydro-...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory activity against acetylcholinesterase in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetAcetylcholinesterase(Electric eel)
Abo Akademi University

Curated by ChEMBL
LigandPNGBDBM50289102(CHEMBL2163792 | CHEMBL355821 | 1,2,3,9-Tetrahydro-...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Abo Akademi University

Curated by ChEMBL
LigandPNGBDBM50289102(CHEMBL2163792 | CHEMBL355821 | 1,2,3,9-Tetrahydro-...)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of horse BChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289102(CHEMBL2163792 | CHEMBL355821 | 1,2,3,9-Tetrahydro-...)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCholinesterase(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50289102(CHEMBL2163792 | CHEMBL355821 | 1,2,3,9-Tetrahydro-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289102(CHEMBL2163792 | CHEMBL355821 | 1,2,3,9-Tetrahydro-...)
Affinity DataIC50: 2.37E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50289102(CHEMBL2163792 | CHEMBL355821 | 1,2,3,9-Tetrahydro-...)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed