BDBM50289218 1,3-Bis-benzo[1,3]dioxol-5-yl-5-benzyloxy-1H-indole-2-carboxylic acid::CHEMBL10136

SMILES OC(=O)c1c(-c2ccc3OCOc3c2)c2cc(OCc3ccccc3)ccc2n1-c1ccc2OCOc2c1

InChI Key InChIKey=XJEFQVHNUODKBN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289218   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289218(1,3-Bis-benzo[1,3]dioxol-5-yl-5-benzyloxy-1H-indol...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory concentration to the endothelin A receptor expressed in LtK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289218(1,3-Bis-benzo[1,3]dioxol-5-yl-5-benzyloxy-1H-indol...)
Affinity DataIC50: 1.40E+4nMAssay Description:Compound was evaluated for binding affinity against human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article