BDBM50289224 1-Benzo[1,3]dioxol-5-ylmethyl-3-(3,4-dimethoxy-phenyl)-5,6-dimethoxy-1H-indole-2-carboxylic acid::CHEMBL10019

SMILES COc1ccc(cc1OC)-c1c(C(O)=O)n(Cc2ccc3OCOc3c2)c2cc(OC)c(OC)cc12

InChI Key InChIKey=OVPKPOGJHFVIFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289224   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289224(1-Benzo[1,3]dioxol-5-ylmethyl-3-(3,4-dimethoxy-phe...)
Affinity DataIC50: 850nMAssay Description:Compound was evaluated for binding affinity against human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289224(1-Benzo[1,3]dioxol-5-ylmethyl-3-(3,4-dimethoxy-phe...)
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration to the endothelin A receptor expressed in LtK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article