BDBM50289229 1,3-Bis-benzo[1,3]dioxol-5-yl-5,6-dimethoxy-1H-indole-2-carboxylic acid::CHEMBL274368

SMILES COc1cc2c(c(C(O)=O)n(-c3ccc4OCOc4c3)c2cc1OC)-c1ccc2OCOc2c1

InChI Key InChIKey=XSMIQRFUKYUGQY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289229   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289229(1,3-Bis-benzo[1,3]dioxol-5-yl-5,6-dimethoxy-1H-ind...)
Affinity DataIC50: 7.00E+3nMAssay Description:Compound was evaluated for binding affinity against human Endothelin B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289229(1,3-Bis-benzo[1,3]dioxol-5-yl-5,6-dimethoxy-1H-ind...)
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration to the endothelin A receptor expressed in LtK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article