BDBM50289320 5-(4-Methanesulfonyl-phenyl)-6-(3-methoxy-phenyl)-thiazolo[3,2-b][1,2,4]triazole::CHEMBL347378

SMILES COc1cccc(c1)-c1c(sc2ncnn12)-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=FGBHTDXMLNCJCI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289320   

TargetProstaglandin G/H synthase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289320(5-(4-Methanesulfonyl-phenyl)-6-(3-methoxy-phenyl)-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Tested in vitro for the ability to inhibit Prostaglandin G/H synthase 1 in chinese hamster ovary (CHO) cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289320(5-(4-Methanesulfonyl-phenyl)-6-(3-methoxy-phenyl)-...)
Affinity DataIC50: 260nMAssay Description:In vivo ability to inhibit Prostaglandin G/H synthase 2 in human whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetProstaglandin G/H synthase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289320(5-(4-Methanesulfonyl-phenyl)-6-(3-methoxy-phenyl)-...)
Affinity DataIC50: 2.57E+8nMAssay Description:Inhibition of COX2 (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article