BDBM50289564 (R)-1-(3-Chloro-phenyl)-2-{(R)-2-[4-(2-hydroxy-ethoxy)-phenyl]-1-methyl-ethylamino}-ethanol::CHEMBL41113

SMILES C[C@H](Cc1ccc(OCCO)cc1)NC[C@H](O)c1cccc(Cl)c1

InChI Key InChIKey=FSOBGMBQSLWEPZ-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50289564   

TargetBeta-3 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289564((R)-1-(3-Chloro-phenyl)-2-{(R)-2-[4-(2-hydroxy-eth...)
Affinity DataEC50:  750nMAssay Description:Effective concentration for stimulation of adenylyl cyclase activity in CHO-beta3 AR expressing cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-2 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289564((R)-1-(3-Chloro-phenyl)-2-{(R)-2-[4-(2-hydroxy-eth...)
Affinity DataKi:  260nMAssay Description:Ability to bind to human Beta-2 adrenergic receptor using membranes of stably transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-1 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289564((R)-1-(3-Chloro-phenyl)-2-{(R)-2-[4-(2-hydroxy-eth...)
Affinity DataKi:  1.25E+3nMAssay Description:Ability to bind to human Beta-1 adrenergic receptor using membranes of stably transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-3 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289564((R)-1-(3-Chloro-phenyl)-2-{(R)-2-[4-(2-hydroxy-eth...)
Affinity DataKi:  2.14E+3nMAssay Description:Ability to bind to human Beta-3 adrenergic receptor using membranes of stably transfected CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article