BDBM50289737 4-(2,4-Dimethoxy-phenyl)-6-ethoxy-1-(2-methoxy-benzyl)-2-oxo-1,2-dihydro-quinoline-3-carboxylic acid::CHEMBL55666

SMILES CCOc1ccc2n(Cc3ccccc3OC)c(=O)c(C(O)=O)c(-c3ccc(OC)cc3OC)c2c1

InChI Key InChIKey=OBDYUWQKVMPPJI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289737   

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50289737(4-(2,4-Dimethoxy-phenyl)-6-ethoxy-1-(2-methoxy-ben...)
Affinity DataIC50: 540nMAssay Description:Inhibition of [125I]ET1 binding to porcine kidney inner medulla membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetEndothelin-1 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50289737(4-(2,4-Dimethoxy-phenyl)-6-ethoxy-1-(2-methoxy-ben...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of [125I]ET1 binding to rat aorta membranes(ETA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article