BDBM50290125 CHEMBL4172914

SMILES Fc1ccc(CN2CCc3nc(nc(NCCCN4CCCC4)c3C2)-c2ccccn2)cc1

InChI Key InChIKey=CARULDOHJPHGLW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50290125   

TargetCystic fibrosis transmembrane conductance regulator(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50290125(CHEMBL4172914)
Affinity DataEC50:  200nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed