BDBM50290141 CHEMBL3746547

SMILES COc1ccc(CN2CCc3nc(nc(NCCCn4ccnc4)c3C2)-c2ccccn2)cc1

InChI Key InChIKey=BPZKEJNQZHOLFN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50290141   

LigandPNGBDBM50290141(CHEMBL3746547)
Affinity DataEC50:  200nMAssay Description:Corrector activity at human CFTR F508 deletion mutant expressed in FRT cells incubated for 25 mins with forskolin by YFP-based fluorescence analysis ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50290141(CHEMBL3746547)
Affinity DataEC50:  200nMAssay Description:Corrector activity at CFTR F508-del mutant (unknown origin) expressed in human CFBE41o cells harboring HS-YFP preincubated for 24 hrs followed by for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/28/2020
Entry Details Article
PubMed