BDBM50290425 CHEMBL57581::[4-(4-Chloro-phenyl)-pyrimidin-2-yl]-[3-(1,1,2,2-tetrafluoro-ethoxy)-phenyl]-amine

SMILES FC(F)C(F)(F)Oc1cccc(Nc2nccc(n2)-c2ccc(Cl)cc2)c1

InChI Key InChIKey=YWEZKJXXUFLVIU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50290425   

TargetProtein kinase C alpha type(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290425([4-(4-Chloro-phenyl)-pyrimidin-2-yl]-[3-(1,1,2,2-t...)
Affinity DataIC50: 850nMAssay Description:Inhibition of protein kinase C alpha.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290425([4-(4-Chloro-phenyl)-pyrimidin-2-yl]-[3-(1,1,2,2-t...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of c-Src-tyrosine kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290425([4-(4-Chloro-phenyl)-pyrimidin-2-yl]-[3-(1,1,2,2-t...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of the epidermal growth factor receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetProtein kinase C delta type(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290425([4-(4-Chloro-phenyl)-pyrimidin-2-yl]-[3-(1,1,2,2-t...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of protein kinase C delta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetTyrosine-protein kinase ABL1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290425([4-(4-Chloro-phenyl)-pyrimidin-2-yl]-[3-(1,1,2,2-t...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290425([4-(4-Chloro-phenyl)-pyrimidin-2-yl]-[3-(1,1,2,2-t...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290425([4-(4-Chloro-phenyl)-pyrimidin-2-yl]-[3-(1,1,2,2-t...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of protein kinase A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article