BDBM50290427 CHEMBL56359::Thiophene-2-carboxylic acid [3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-amide

SMILES O=C(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)c1cccs1

InChI Key InChIKey=MWZFSVMDXHMRHG-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50290427   

TargetTyrosine-protein kinase ABL1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290427(Thiophene-2-carboxylic acid [3-(4-pyridin-3-yl-pyr...)
Affinity DataIC50: 300nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEpidermal growth factor receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50290427(Thiophene-2-carboxylic acid [3-(4-pyridin-3-yl-pyr...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of the epidermal growth factor receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290427(Thiophene-2-carboxylic acid [3-(4-pyridin-3-yl-pyr...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of c-Src-tyrosine kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290427(Thiophene-2-carboxylic acid [3-(4-pyridin-3-yl-pyr...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of protein kinase A.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

LigandPNGBDBM50290427(Thiophene-2-carboxylic acid [3-(4-pyridin-3-yl-pyr...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article