BDBM50291163 4-Phenyl-1-{(S)-2-[(R)-2-(thiazole-2-carbonyl)-pyrrolidine-1-carbonyl]-pyrrolidin-1-yl}-butan-1-one::CHEMBL436620

SMILES O=C(CCCc1ccccc1)N1CCC[C@H]1C(=O)N1CCC[C@@H]1C(=O)c1nccs1

InChI Key InChIKey=LPDUJIYPFMOVDG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50291163   

TargetProlyl endopeptidase(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50291163(4-Phenyl-1-{(S)-2-[(R)-2-(thiazole-2-carbonyl)-pyr...)
Affinity DataIC50: 4.40nMAssay Description:The compound was tested for the inhibitory activity against prolyl endo peptidase(PEP) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProthrombin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291163(4-Phenyl-1-{(S)-2-[(R)-2-(thiazole-2-carbonyl)-pyr...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetSerine protease 1(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50291163(4-Phenyl-1-{(S)-2-[(R)-2-(thiazole-2-carbonyl)-pyr...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/28/2012
Entry Details Article

TargetProlyl endopeptidase(Pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50291163(4-Phenyl-1-{(S)-2-[(R)-2-(thiazole-2-carbonyl)-pyr...)
Affinity DataIC50: 6.02E+3nMAssay Description:In vitro inhibitory activity against prolyl endopeptidase (PEP)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed