BDBM50291262 CHEMBL4164541

SMILES CCc1nc2c(ccnc2n1Cc1cccc(Cl)c1)N1CCNCC1

InChI Key InChIKey=UDRACXACDCFKNK-UHFFFAOYSA-N

Data  5 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50291262   

Target5-hydroxytryptamine receptor 6(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50291262(CHEMBL4164541)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]-LSD from human 5HT6R expressed in HEK293 cell membranes after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50291262(CHEMBL4164541)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at 5HT6R (unknown origin) transfected in NG108-15 cells co-transfected with CAMYEL assessed as reduction in cAMP levels after 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50291262(CHEMBL4164541)
Affinity DataKi:  449nMAssay Description:Displacement of [3H]-Ketanserin from human 5HT2AR expressed in CHO-K1 cell membranes after 1.5 hrs by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50291262(CHEMBL4164541)
Affinity DataKi:  1.35E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5HT1AR expressed in HEK293 cell membranes after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50291262(CHEMBL4164541)
Affinity DataKi:  6.10E+3nMAssay Description:Displacement of [3H]-Raclopride from human dopamine D2L receptor expressed in HEK293 cell membranes after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50291262(CHEMBL4164541)
Affinity DataKi:  8.75E+3nMAssay Description:Displacement of [3H]-5-CT from human 5HT7BR expressed in HEK293 cell membranes after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2020
Entry Details Article
PubMed