BDBM50291491 3-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-vinyl]-thiophene-2-sulfonic acid (4-bromo-3-methyl-isoxazol-5-yl)-amide::CHEMBL176854

SMILES Cc1noc(NS(=O)(=O)c2sccc2\C=C\c2cc3OCOc3cc2C)c1Br

InChI Key InChIKey=NNAQTUFNGOEBBT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50291491   

TargetEndothelin-1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291491(3-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-vinyl]-thiop...)
Affinity DataIC50: 72nMAssay Description:Tested for the inhibitory activity of cloned human ETA receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetEndothelin receptor type B(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50291491(3-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-vinyl]-thiop...)
Affinity DataIC50: 5.37E+3nMAssay Description:Tested for the inhibitory activity of cloned human ETB receptor by using I-ET-1 as radioligand in a competitive radioligand assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article