BDBM50291878 CHEMBL4161839

SMILES CCOC(=O)CSc1nc(Oc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(N)=O)c(C#N)c(n1)-c1ccc(F)cc1

InChI Key InChIKey=WNEBSXIACMMFKQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50291878   

TargetSerine/threonine-protein kinase Chk2(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50291878(CHEMBL4161839)
Affinity DataIC50: 32nMAssay Description:Inhibition of Chk2 (unknown origin) assessed as decrease in Cdc25C phosphorylation at Ser216 by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2020
Entry Details Article
PubMed