BDBM50292278 CHEMBL4174271

SMILES CCN1CCN(CC1)c1nc(C)nc2oc(nc12)-c1ccccc1Cl

InChI Key InChIKey=XWYLNWVTWBTYTQ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50292278   

TargetCannabinoid receptor 2(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50292278(CHEMBL4174271)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 expressed in CHO cells after 90 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50292278(CHEMBL4174271)
Affinity DataIC50: 120nMAssay Description:Neutral antagonist activity at human CB2 assessed as restoration of forskolin-induced cAMP formation preincubated for 15 mins followed by forskolin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50292278(CHEMBL4174271)
Affinity DataIC50: 120nMAssay Description:Neutral antagonist activity at human CB2 assessed as inhibition of WIN552122-induced suppression of cAMP formation preincubated for 15 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Univ. Lille

Curated by ChEMBL
LigandPNGBDBM50292278(CHEMBL4174271)
Affinity DataKi:  293nMAssay Description:Displacement of [3H]-CP-55940 from human CB1 expressed in CHO cells after 90 mins by TopCount scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2020
Entry Details Article
PubMed