BDBM50292365 CHEMBL4160383

SMILES Cc1ccc(cc1)-c1nc(S)nc(Sc2ccc(cc2)-c2nc3cc(ccc3[nH]2)C(N)=O)c1C#N

InChI Key InChIKey=YKTRRSNITRLXSD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50292365   

TargetSerine/threonine-protein kinase Chk2(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50292365(CHEMBL4160383)
Affinity DataIC50: 36nMAssay Description:Inhibition of Chk2 (unknown origin) assessed as decrease in Cdc25C phosphorylation at Ser216 by ELISA based spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2020
Entry Details Article
PubMed