BDBM50292747 1-[(3-{[(Pyridin-4-ylmethyl)amino]methyl}benzyl)amino]ethaniminium bromide::CHEMBL490870

SMILES C\C(N)=[NH+]\Cc1cccc(CNCc2ccncc2)c1

InChI Key InChIKey=GJXJTSVAMDBELG-UHFFFAOYSA-O

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292747   

TargetNitric oxide synthase, inducible(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292747(1-[(3-{[(Pyridin-4-ylmethyl)amino]methyl}benzyl)am...)
Affinity DataIC50: 350nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292747(1-[(3-{[(Pyridin-4-ylmethyl)amino]methyl}benzyl)am...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed