BDBM50292748 1-{[3-({[(4-Methylphenyl)sulfonyl]amino}methyl)benzyl]amino}ethaniminium chloride::CHEMBL490886

SMILES C\C(N)=[NH+]\Cc1cccc(CNS(=O)(=O)c2ccc(C)cc2)c1

InChI Key InChIKey=HRGKQLBKMDIDKN-UHFFFAOYSA-O

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292748   

TargetNitric oxide synthase, inducible(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292748(1-{[3-({[(4-Methylphenyl)sulfonyl]amino}methyl)ben...)
Affinity DataIC50: 500nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292748(1-{[3-({[(4-Methylphenyl)sulfonyl]amino}methyl)ben...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline pre-incubated 1 hr ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed