BDBM50292927 (+/-)-2-benzyl-1-(3,5-dichlorophenyl)-3-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)propane-1,3-dione::CHEMBL489097

SMILES COc1cc2CCN(Cc2cc1OC)C(=O)C(Cc1ccccc1)C(=O)c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=WJWAVTWCDWTTCP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292927   

TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292927((+/-)-2-benzyl-1-(3,5-dichlorophenyl)-3-(6,7-dimet...)
Affinity DataIC50: 5.30E+3nMAssay Description:Antagonist activity at human OX1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292927((+/-)-2-benzyl-1-(3,5-dichlorophenyl)-3-(6,7-dimet...)
Affinity DataIC50: 36nMAssay Description:Antagonist activity at human OX2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed