BDBM50292930 CHEMBL454924::N-(cyclopropylmethyl)-2-(1-(3,4-difluorophenethyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-2-phenylacetamide

SMILES COc1cc2CCN(C(C(=O)NCC3CC3)c3ccccc3)C(CCc3ccc(F)c(F)c3)c2cc1OC

InChI Key InChIKey=MGTLLLVBSOYCAX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292930   

TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292930(N-(cyclopropylmethyl)-2-(1-(3,4-difluorophenethyl)...)
Affinity DataIC50: 552nMAssay Description:Inhibition of OX1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292930(N-(cyclopropylmethyl)-2-(1-(3,4-difluorophenethyl)...)
Affinity DataIC50: 14nMAssay Description:Inhibition of OX2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed