BDBM50292933 CHEMBL490082::N-cyclopropyl-2-(6,7-dimethoxy-1-(naphthalen-2-ylmethyl)-3,4-dihydroisoquinolin-2(1H)-yl)-2-phenylacetamide

SMILES COc1cc2CCN(C(C(=O)NC3CC3)c3ccccc3)C(Cc3ccc4ccccc4c3)c2cc1OC

InChI Key InChIKey=RWSZLMVCERHQGM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50292933   

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292933(N-cyclopropyl-2-(6,7-dimethoxy-1-(naphthalen-2-ylm...)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at OX1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292933(N-cyclopropyl-2-(6,7-dimethoxy-1-(naphthalen-2-ylm...)
Affinity DataIC50: 80nMAssay Description:Antagonist activity at OX2R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292933(N-cyclopropyl-2-(6,7-dimethoxy-1-(naphthalen-2-ylm...)
Affinity DataIC50: 37nMAssay Description:Inhibition of OX1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292933(N-cyclopropyl-2-(6,7-dimethoxy-1-(naphthalen-2-ylm...)
Affinity DataIC50: 80nMAssay Description:Inhibition of OX2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed