BDBM50292937 CHEMBL451281::N-benzyl-2-(6,7-dimethoxy-1-(3-methoxy-4-(pyrimidin-2-yloxy)benzyl)-3,4-dihydroisoquinolin-2(1H)-yl)acetamide

SMILES COc1cc2CCN(CC(=O)NCc3ccccc3)C(Cc3ccc(Oc4ncccn4)c(OC)c3)c2cc1OC

InChI Key InChIKey=RRBYCHHICVPEJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292937   

TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292937(N-benzyl-2-(6,7-dimethoxy-1-(3-methoxy-4-(pyrimidi...)
Affinity DataIC50: 52nMAssay Description:Inhibition of OX1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292937(N-benzyl-2-(6,7-dimethoxy-1-(3-methoxy-4-(pyrimidi...)
Affinity DataIC50: 240nMAssay Description:Inhibition of OX2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed