BDBM50292939 CHEMBL489485::N-benzyl-2-(1-(3,4-dichlorobenzyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)acetamide

SMILES COc1cc2CCN(CC(=O)NCc3ccccc3)C(Cc3ccc(Cl)c(Cl)c3)c2cc1OC

InChI Key InChIKey=FIPKTJXYARUTNO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50292939   

TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292939(N-benzyl-2-(1-(3,4-dichlorobenzyl)-6,7-dimethoxy-3...)
Affinity DataIC50: 118nMAssay Description:Inhibition of OX1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292939(N-benzyl-2-(1-(3,4-dichlorobenzyl)-6,7-dimethoxy-3...)
Affinity DataIC50: 118nMAssay Description:Antagonist activity at OX1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292939(N-benzyl-2-(1-(3,4-dichlorobenzyl)-6,7-dimethoxy-3...)
Affinity DataIC50: 281nMAssay Description:Antagonist activity at OX2R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292939(N-benzyl-2-(1-(3,4-dichlorobenzyl)-6,7-dimethoxy-3...)
Affinity DataIC50: 281nMAssay Description:Inhibition of OX2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed